The essence of Kamagra lies in the active substance Sildenafil, which is also the key ingredient of the most well-known medication for erectile dysfunction – Viagra. Sildenafil acts as an inhibitor of the enzyme phosphodiesterase type 5 and is used for the treatment of erectile dysfunction. This ingredient and its unique abilities were discovered by researchers Andrew Bell, David Brown, and Nicholas Terrett at the American corporation Pfizer. Sildenafil was the first such active substance on the market, and later, copies emerged (vardenafil, tadalafil – Cialis, avanafil, etc.). Tablets of 25, 50, and 100 mg are usually available on the market.
In the case of Kamagra, the choice is wide-ranging because of fruit gels, chewable candies, and effervescent tablets, alongside classic blue pills. As with other products for a stronger and firmer erection, the action of the product requires prior sexual arousal of the man. The drug itself does not induce sexual arousal. When a man is adequately sexually stimulated, the release of nitric oxide (NO) into the soft muscle tissue of the blood vessels in the penis begins, which activates the substance GC (guanylate cyclase).
The result is an increase in the production of the substance cGMP (cyclic guanosine monophosphate), which causes dilation (widening) of the blood vessel cells. Since Sildenafil prevents the action of the enzyme PDE5, which further prevents the breakdown of the substance cGMP, the result of this mechanism is well-known to all users of Kamagra – a firm, strong, and long-lasting erection.